Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates
Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice Meter JM-105 for the screening of neonatal jaundice in Malay neonates. Methods: Prospective cross-sectional study cond...
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my-usm-ep.588502023-07-06T06:46:26Z Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates 2021 Mohamed, Mazrah RJ Pediatrics Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice Meter JM-105 for the screening of neonatal jaundice in Malay neonates. Methods: Prospective cross-sectional study conducted in a tertiary university hospital involving 130 jaundiced neonates who required serum bilirubin determination from day 2 to day 7 of life. Paired bilirubin samples of total serum bilirubin (TSB) and transcutaneous bilirubin (TcB) were obtained. TcB were measured at the neonates’ forehead and sternum. The TcB were measured using JM-105. Results: There were 130 paired samples of TSB and TcB. The mean TSB was 232 μmol/L. The mean TcB measured at forehead and sternum were 222 μmol/L and 223 μmol/L, respectively. The mean difference between TSB and TcB was 10 μmol/L at forehead and 9 μmol/L at sternum. Strong positive correlation between TSB with mean TcB forehead (r=0.82) and TcB sternum (r=0.80), and strong correlation (r=0.91) between TcB forehead and TcB sternum. Conclusion: Our study demonstrated strong correlation between TcB values and TSB values. TcB measured at forehead or sternum is a good alternative as a non-invasive screening tool for non-severe hyperbilirubinemia in Malay neonates. 2021 Thesis http://eprints.usm.my/58850/ http://eprints.usm.my/58850/1/MAZRAH%20BINTI%20MOHAMED-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
RJ Pediatrics |
| spellingShingle |
RJ Pediatrics Mohamed, Mazrah Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| description |
Background: Transcutaneous bilirubinometer is a portable, painless and non-invasive
device to measure bilirubin. This study aims to investigate the reliability of Dräger Jaundice
Meter JM-105 for the screening of neonatal jaundice in Malay neonates.
Methods: Prospective cross-sectional study conducted in a tertiary university hospital
involving 130 jaundiced neonates who required serum bilirubin determination from day 2 to day
7 of life. Paired bilirubin samples of total serum bilirubin (TSB) and transcutaneous bilirubin
(TcB) were obtained. TcB were measured at the neonates’ forehead and sternum. The TcB were
measured using JM-105.
Results: There were 130 paired samples of TSB and TcB. The mean TSB was 232
μmol/L. The mean TcB measured at forehead and sternum were 222 μmol/L and 223 μmol/L,
respectively. The mean difference between TSB and TcB was 10 μmol/L at forehead and 9
μmol/L at sternum. Strong positive correlation between TSB with mean TcB forehead (r=0.82)
and TcB sternum (r=0.80), and strong correlation (r=0.91) between TcB forehead and TcB
sternum.
Conclusion: Our study demonstrated strong correlation between TcB values and TSB
values. TcB measured at forehead or sternum is a good alternative as a non-invasive screening
tool for non-severe hyperbilirubinemia in Malay neonates. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Mohamed, Mazrah |
| author_facet |
Mohamed, Mazrah |
| author_sort |
Mohamed, Mazrah |
| title |
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| title_short |
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| title_full |
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| title_fullStr |
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| title_full_unstemmed |
Comparison Between Transcutaneous and Total Serum Bilirubin Measurement in Malay Neonates |
| title_sort |
comparison between transcutaneous and total serum bilirubin measurement in malay neonates |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Pengajian Sains Perubatan |
| publishDate |
2021 |
| url |
http://eprints.usm.my/58850/1/MAZRAH%20BINTI%20MOHAMED-24%20pages.pdf |
| _version_ |
1776101238362865664 |