Structural analysis of platelet-derived growth factor receptor alpha by protein homology modeling

Constitutive phosphorylation activity by receptor tyrosine kinases due to activating mutations have been linked to human malignancies. Substitution mutation of tyrosine 849 to serine residue led to the constitutive phosphorylation of platelet-derived growth factor receptor alpha (PDGFRa) as found in...

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Bibliographic Details
Main Author: Hussin, Nurulfarhana
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://eprints.utm.my/id/eprint/54058/25/NurulfarhanaHussinMFBME2015.pdf
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